Κατηγορία: Άρθρα

Clinical and surgical-pathological staging in early non-small cell lung cancer

Staging is of the utmost importance in the evaluation of a patientwith non-small cell lung cancer (NSCLC) because it defines the actualextent of the disease. Accurate staging allows multidisciplinaryoncology teams to plan the best surgical or medical treatment and topredict patient prognosis. Based on the recommendation of theInternational Association for the Study of Lung Cancer […]

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Soluble ICAM-1 levels in small-cell lung cancer

Intercellular adhesion molecule-1 (ICAM-1) isan adhesion molecule, member of the immunoglobulingene superfamily that seems to participate in the evolutionof the metastatic process. We investigated the significanceof baseline soluble ICAM-1 levels on the outcome ofpatients with small-cell lung cancer and whether solubleICAM-1 is a predictive marker for objective responseduring and after chemotherapy in patients with small-celllung […]

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Histones and lung cancer

Purpose Deoxyribonucleic acid is wrapped around anoctamer of core histone proteins to form a nucleosome, thebasic structure of chromatin. Two main families ofenzymes maintain the equilibrium of acetyl groups addedto or removed from lysine residues. Histone deacetylases(HDACs) catalyze the removal of acetyl groups fromlysine residues in histone amino termini and non-histoneproteins also, leading to chromatin […]

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The clinical significance of smoking cessation in patients with cancer

Florou A¹, Gkiozos I², Syrigos K³1. Respiratory Physician, Pulmonary and Critical Care Department, Athens Medical School, “Evgenidion” Hospital2. Respiratory Physician, Oncology Unit G’PP, Athens, Medical School,“Sotiria” General  Hospital3. Associate Professor of Clinical Oncology, Head of Oncology Unit G’PP, Athens, Medical School, “Sotiria” General Hospital Introduction: Despite the established causal relationship between tobacco smoking and cancer […]

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